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Head-to-head · Cost-Efficiency Index

CaliberRx vs Curve

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #189

CaliberRx

Shoppers who want simple flat-rate pricing and a clear, published list of excluded states.

Visit CaliberRx
VS
Grade C · #192

Curve

Cost-first shoppers who want legitScript-certified compounded GLP-1 at flat per-dose pricing.

Visit Curve

The verdict

Too close to callGrade C vs C

CaliberRx and Curve tie on the Cost-Efficiency Index at 63/100, so neither wins outright on the numbers. For most shoppers we'd start with CaliberRx (ranked #189, a hair above #192) — Shoppers who want simple flat-rate pricing and a clear, published list of excluded states. But Curve is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs CaliberRx.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

57
57

Price Transparency

94
68

Nationwide Access

24
86

Formulation Options

66
66

Clinical Oversight

88
68

Contract Flexibility

47
20

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCaliberRxCurve
Cost-Efficiency Index63/10063/100
Semaglutide / mo$199/mo (all doses, compounded)$175/mo (compounded)
Tirzepatide / mo$199/mo (all doses, compounded)$225/mo (compounded)
Semaglutide / yr (modeled)$2,388$2,100
Tirzepatide / yr (modeled)$2,388$2,700
CoverageCoverage not publishedAll 50 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#189#192

CaliberRx

63/100

Where the value is

  • Flat, identical $199/month pricing for both semaglutide and tirzepatide -- no confusing dose tiers to compare
  • No prepay or first-month-only trap detected on the pages checked
  • LegitScript certification verifiably linked

The tradeoffs

  • No individual medical director named
  • No compounding pharmacy named
Visit CaliberRx

Full CaliberRx review →

Curve

63/100

Where the value is

  • Offers both compounded semaglutide and tirzepatide, with every dose priced the same so cost does not rise as you titrate up.
  • LegitScript-certified (seal #51079066) and names both its 503A compounding pharmacy, VialsRx, and its provider network, Beluga Health.
  • Transparent tiered pricing with a real month-to-month option; consultation, medication, and free expedited shipping included, no membership.

The tradeoffs

  • Very new (2026 launch) with a thin track record; the site still shows a Webflow template credit and a leftover Cora reference in its Terms.
  • The cheapest headline rates ($99 semaglutide / $135 tirzepatide) require a 12-month prepay; true month-to-month is $175 and $225.
Visit Curve

Full Curve review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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