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Head-to-head · Cost-Efficiency Index

Beluga Health vs Defy Medical

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #490

Beluga Health

Cost-first shoppers who want not applicable to consumers -- this is a B2B platform, not a GLP-1 provider a shopper can buy from directly.

Visit Beluga Health
VS
Grade C · #492

Defy Medical

Cost-first shoppers who want existing or prospective TRT/men's-health patients wanting to add GLP-1 to an established hormone-optimization relationship -- not the first stop for a shopper solely comparing dedicated GLP-1 weight-loss pricing.

Visit Defy Medical

The verdict

Too close to callGrade C vs C

Beluga Health and Defy Medical tie on the Cost-Efficiency Index at 43/100, so neither wins outright on the numbers. For most shoppers we'd start with Beluga Health (ranked #490, a hair above #492) — Cost-first shoppers who want not applicable to consumers -- this is a B2B platform, not a GLP-1 provider a shopper can buy from directly. But Defy Medical is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Beluga Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
45

Price Transparency

30
20

Nationwide Access

24
24

Formulation Options

40
56

Clinical Oversight

76
80

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecBeluga HealthDefy Medical
Cost-Efficiency Index43/10043/100
Semaglutide / moNot disclosedNot disclosed
Tirzepatide / moNot disclosedNot disclosed
Semaglutide / yr (modeled)
Tirzepatide / yr (modeled)
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyCompounded only
Rank here#490#492

Beluga Health

43/100

Where the value is

  • Physician network led by a named, board-certified medical doctor licensed in all 50 states + DC
  • Claims LegitScript-certified physician network
  • Powers multiple consumer weight-loss brands, suggesting operational scale

The tradeoffs

  • Not a consumer-facing product -- no way to buy semaglutide or tirzepatide directly from this site
  • No pricing, dosing, or plan information published anywhere
Visit Beluga Health

Full Beluga Health review →

Defy Medical

43/100

Where the value is

  • Named, credentialed Medical Director (Dr. Justin Saya)
  • Large third-party review base (3,999 Trustpilot reviews, 5-star average)
  • Offers both semaglutide and tirzepatide alongside broader men's-health services

The tradeoffs

  • GLP-1 is clearly a secondary offering bolted onto a primarily TRT/hormone-optimization practice, not its core focus
  • Zero pricing disclosed anywhere on the public site -- fully gated behind quiz/consultation
Visit Defy Medical

Full Defy Medical review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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