Head-to-head · Cost-Efficiency Index
Avono Health vs TeleWellnessMD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Avono Health
Shoppers specifically wanting an oral-capsule semaglutide option and willing to prepay a full quarter.
Visit Avono HealthTeleWellnessMD
Cost-first shoppers who want not recommended based on headline pricing alone -- always price out the Month 4-5+ maintenance dose before comparing.
Visit TeleWellnessMDThe verdict
Avono Health and TeleWellnessMD tie on the Cost-Efficiency Index at 49/100, so neither wins outright on the numbers. For most shoppers we'd start with Avono Health (ranked #419, a hair above #426) — Shoppers specifically wanting an oral-capsule semaglutide option and willing to prepay a full quarter. But TeleWellnessMD is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Avono Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Avono Health | TeleWellnessMD |
|---|---|---|
| Cost-Efficiency Index | 49/100 | 49/100 |
| Semaglutide / mo | $699/mo (3-month plan, compounded) | $349/mo (0.25 mg dose, compounded) |
| Tirzepatide / mo | Not disclosed | $679/mo (2.5 mg dose, compounded) |
| Semaglutide / yr (modeled) | $8,388 | $4,188 |
| Tirzepatide / yr (modeled) | — | $8,148 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #419 | #426 |
Avono Health
49/100Where the value is
- Offers a genuinely rare oral-capsule semaglutide format, not just injectable
- Transparent that pricing is a 3-month bundle rather than hiding the prepay structure
- US-nationwide clinician network claimed
The tradeoffs
- 'Saves $X vs. monthly' claims can't be verified since the standalone monthly price is never disclosed
- No tirzepatide offering at all -- semaglutide only
TeleWellnessMD
49/100Where the value is
- Broad GLP-1/GIP product catalog with add-on B-vitamin combination options
- Nationwide state-selector covers all 50 states plus Puerto Rico (with unspecified exceptions)
- Transparent month-by-month price table is at least published in full, not hidden behind a quote wall
The tradeoffs
- Headline prices ($199.95 / $279.95) are lowest-starter-dose only, not the real maintenance cost
- Maintenance-dose pricing is 75-140% higher than the advertised entry price
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.