Head-to-head · Cost-Efficiency Index
24hrDOC vs Ascend Medical
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
24hrDOC
Shoppers comparing the ongoing standing price of compounded GLP-1s, not the first-month promotional rate.
Visit 24hrDOCAscend Medical
Cost-first shoppers who want georgia or Texas residents who want to bill GLP-1 treatment through insurance rather than pay cash-only compounded pricing.
Visit Ascend MedicalThe verdict
24hrDOC and Ascend Medical tie on the Cost-Efficiency Index at 57/100, so neither wins outright on the numbers. For most shoppers we'd start with 24hrDOC (ranked #296, a hair above #299) — Shoppers comparing the ongoing standing price of compounded GLP-1s, not the first-month promotional rate. But Ascend Medical is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs 24hrDOC.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | 24hrDOC | Ascend Medical |
|---|---|---|
| Cost-Efficiency Index | 57/100 | 57/100 |
| Semaglutide / mo | $249/mo (microdose tier, 2 mg dose, compounded) | Not disclosed |
| Tirzepatide / mo | $339/mo (microdose tier, starting dose, compounded) | $240/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $2,988 | — |
| Tirzepatide / yr (modeled) | $4,068 | $2,880 |
| Coverage | Coverage not published | 2 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #296 | #299 |
24hrDOC
57/100Where the value is
- Full struck-through pricing (promo vs. regular) is published on-site before intake, so the true ongoing cost is verifiable rather than hidden
- Both standard and lower-cost microdose options published for each drug
- Fast intake model: '10-minute assessment' with no office visit required
The tradeoffs
- The widely-advertised $149/$239 price is a ONE-TIME first-month discount ('$100 off'); the standing ongoing price is $249/mo semaglutide and $339/mo tirzepatide — about 40% higher
- No compounding pharmacy or medical director named on the site
Regulatory note: the FDA issued a warning letter to 24HrDoc, Inc. dba 24HrDoc in February 2026. We still list and link to 24hrDOC; you should know the letter is on the public record before you decide.
Ascend Medical
57/100Where the value is
- Can bill through insurance, potentially lowering out-of-pocket cost versus cash-only compounded programs
- No-subscription, pay-per-refill model after the initial 8-week package
- Named metabolic-health chair referenced on the clinical team
The tradeoffs
- Only available to Georgia and Texas residents -- not a national service
- Unclear whether medication is compounded or brand-name; no compounding pharmacy named
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.