Head-to-head · Cost-Efficiency Index
YourEra vs Brello Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
YourEra
Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Visit YourEraBrello Health
Shoppers comfortable with a mandatory 3-month auto-renewing commitment in exchange for a discounted per-month rate.
Visit Brello HealthThe verdict
Brello Health takes it, leading the Cost-Efficiency Index 64 to 62. Brello Health is a telehealth wellness platform selling compounded semaglutide at a discounted $133/mo (off a stated $198/mo) and tirzepatide at $166/mo (off $247/mo). YourEra still earns a C — Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Brello Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | YourEra | Brello Health |
|---|---|---|
| Cost-Efficiency Index | 62/100 | 64/100 |
| Semaglutide / mo | $179/mo (all doses, month-to-month, compounded) | $133/mo (3-month plan, compounded) |
| Tirzepatide / mo | $259/mo (all doses, month-to-month, compounded) | $166/mo (3-month plan, compounded) |
| Semaglutide / yr (modeled) | $2,148 | $1,596 |
| Tirzepatide / yr (modeled) | $3,108 | $1,992 |
| Coverage | Coverage not published | 35 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #171 | #175 |
YourEra
62/100Where the value is
- A 6-month prepay drops semaglutide to $99/month, among the lowest compounded-GLP-1 headline prices we track
- No membership-fee structure; the site markets "no hidden fees" and "Same price at every dose"
- Prescriptions are "issued only if deemed medically appropriate" after evaluation by licensed US clinicians, stated plainly
The tradeoffs
- The advertised $99/month requires a 6-month prepay — paying month to month costs $149 for the first month and $179/month after, nearly double the headline
- Tirzepatide's advertised $179 is a first-month intro, not a prepay rung: the page's own words are "Month-to-month intro. Then $259/mo." — so the two molecules' headline discounts work in two different ways on one page
Brello Health
64/100Where the value is
- Discount structure is itemized transparently — both the discounted and pre-discount standing price are shown side by side ($133 vs $198 for semaglutide, $166 vs $247 for tirzepatide)
- Bundle options combining GLP-1 with NAD+ and/or Sermorelin are available on the same subscription
- The commitment mechanics are explicitly disclosed on-site ('3-month minimum commitment and automatically renew every 11 weeks') rather than buried in terms of service
The tradeoffs
- No month-to-month option exists at any price — every plan requires a 3-month minimum and auto-renews every 11 weeks, a real commitment a shopper comparing 'per month' prices across sites could easily miss
- The compounding pharmacy is not named, only 'USA-based 503A Partner Pharmacy,' and the site discloses it is mid-transition to a new facility
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.