Head-to-head · Cost-Efficiency Index
Strut Health vs VyrarX
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Strut Health
Anyone optimising total monthly outlay who will keep an auto-refill running, and anyone whose real objection is the needle.
Visit Strut HealthVyrarX
Cost-first shoppers who want compounded semaglutide ($179/mo) and tirzepatide ($329/mo) via LegitScript-certified telehealth in 47 states.
Visit VyrarXThe verdict
Strut Health takes it, leading the Cost-Efficiency Index 87 to 62. The lowest true entry cost on this board — $99/month sublingual semaglutide — and the only place selling the same molecule as a lozenge or an injection at one price. VyrarX still earns a C — Cost-first shoppers who want compounded semaglutide ($179/mo) and tirzepatide ($329/mo) via LegitScript-certified telehealth in 47 states.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Strut Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Strut Health | VyrarX |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 62/100 |
| Semaglutide / mo | From $99/mo sublingual, $149/mo injectable | $179/mo (starting dose, compounded) |
| Tirzepatide / mo | From $199/mo either route | $329/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $1,188 | $2,148 |
| Tirzepatide / yr (modeled) | $2,388 | $3,948 |
| Coverage | 49 states (not Arkansas) | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #4 | #217 |
Strut Health
87/100Where the value is
- Cheapest disclosed monthly cost here at $99/mo for sublingual semaglutide; tirzepatide $199 either route
- Sublingual lozenges for both molecules at the same price as the injection
- Free physician visit, free shipping and free follow-up care included rather than billed separately
The tradeoffs
- The $99 and $149 headline figures require auto-refill — a one-off order costs more, so the true cost depends on staying subscribed
- Asynchronous by design: their FAQ notes some states need no phone consultation, so you may never speak to the prescriber
VyrarX
62/100Where the value is
- LegitScript certified with active seal (ID 51177727)
- Semaglutide starting at $179/month with free shipping included
- 1:1 direct provider messaging and personalized titration plan in every plan
The tradeoffs
- Tirzepatide at $329/month starting is at the high end of the compounded market
- Compounding pharmacy not named on any public page
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.