Head-to-head · Cost-Efficiency Index
ShedRx (Shed) vs YourHealthRx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ShedRx (Shed)
People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.
Visit ShedRx (Shed)YourHealthRx
Cost-first shoppers who want science-forward GLP-1 and peptide care nationwide, with flat-rate dosing and built-in clinical follow-up.
Visit YourHealthRxThe verdict
ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 61. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. YourHealthRx still earns a C — Cost-first shoppers who want science-forward GLP-1 and peptide care nationwide, with flat-rate dosing and built-in clinical follow-up.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ShedRx (Shed) | YourHealthRx |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 61/100 |
| Semaglutide / mo | $199/mo ($159 on a 12-month plan) | $170/mo (compounded) |
| Tirzepatide / mo | $299/mo ($239 on a 12-month plan) | $210/mo (compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,040 |
| Tirzepatide / yr (modeled) | $3,588 | $2,520 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Yes | Compounded only |
| Rank on the board | #3 | #230 |
ShedRx (Shed)
87/100Where the value is
- Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
- Brand Zepbound and Wegovy available alongside the compounded line
- Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee
The tradeoffs
- The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
YourHealthRx
61/100Where the value is
- Available in all 50 states and DC through a multi-state (IMLC) licensed clinician network
- Compounded semaglutide and tirzepatide in two formats - weekly injectable (with B12) or daily oral dissolving tablet
- Flat subscription price that doesn't change as your dose increases (no titration penalty)
The tradeoffs
- Eligibility and prescribing run through partner clinical workflows - YourHealthRx is the platform, not the prescriber or pharmacy
- Compounded medications are not FDA-approved - not brand Wegovy, Ozempic, Zepbound, or Mounjaro
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.