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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs RedBox Rx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #3

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade C · #320

RedBox Rx

People who want flat-rate compounded glp-1 with either injection or oral dosing.

Visit RedBox Rx

The verdict

Winner · ShedRx (Shed)Grade B+ vs C

ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 54. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. RedBox Rx still earns a CPeople who want flat-rate compounded glp-1 with either injection or oral dosing.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
52

Price Transparency

74
46

Nationwide Access

92
24

Formulation Options

96
77

Clinical Oversight

84
97

Contract Flexibility

76
41

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)RedBox Rx
Cost-Efficiency Index87/10054/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$269/mo (all doses, 6-month plan, compounded)
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$429/mo
Semaglutide / yr (modeled)$2,388$3,228
Tirzepatide / yr (modeled)$3,588$5,148
CoverageAll 50 statesCoverage not published
Oral / sublingualYesYes
Brand-name accessYesCompounded only
Rank on the board#3#320

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

RedBox Rx

54/100

Where the value is

  • Flat, dose-independent pricing on both semaglutide and tirzepatide
  • Offers both weekly injections and daily oral tablets
  • Includes unlimited provider follow-ups, a metabolic panel and a dietitian session

The tradeoffs

  • Does not serve every state (for example Mississippi is excluded)
  • Does not publicly name its compounding pharmacy
Visit RedBox Rx

Full RedBox Rx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

Keep comparing

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