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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs Luci

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #3

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade C · #275

Luci

Cost-first shoppers who want budget shoppers wanting low-cost compounded semaglutide or tirzepatide, including oral pill options.

Visit Luci

The verdict

Winner · ShedRx (Shed)Grade B+ vs C

ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 57. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. Luci still earns a CCost-first shoppers who want budget shoppers wanting low-cost compounded semaglutide or tirzepatide, including oral pill options.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
86

Price Transparency

74
30

Nationwide Access

92
24

Formulation Options

96
77

Clinical Oversight

84
72

Contract Flexibility

76
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)Luci
Cost-Efficiency Index87/10057/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$99/mo (starting dose, promotional rate, compounded)
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$145/mo (starting dose, promotional rate, compounded)
Semaglutide / yr (modeled)$2,388$1,188
Tirzepatide / yr (modeled)$3,588$1,740
CoverageAll 50 statesCoverage not published
Oral / sublingualYesYes
Brand-name accessYesCompounded only
Rank on the board#3#275

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

Luci

57/100

Where the value is

  • Budget-friendly compounded GLP-1 pricing (compounded semaglutide as low as $99/month, tirzepatide as low as $145/month)
  • Multiple formats: compounded semaglutide and tirzepatide injections plus oral semaglutide and tirzepatide pill kits
  • Upfront pricing with no insurance required and a fast 3-minute questionnaire to start

The tradeoffs

  • Compounded medications are not FDA-approved for weight loss (the site discloses this) — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
  • Available only in select U.S. states, and the full state list is not published
Visit Luci

Full Luci review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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