Head-to-head · Cost-Efficiency Index
ShedRx (Shed) vs Good Girl Rx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ShedRx (Shed)
People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.
Visit ShedRx (Shed)Good Girl Rx
Patients seeking multiple compounded GLP-1 formats with pharmacy quality standards.
Visit Good Girl RxThe verdict
ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 68. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. Good Girl Rx still earns a C — Patients seeking multiple compounded GLP-1 formats with pharmacy quality standards.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ShedRx (Shed) | Good Girl Rx |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 68/100 |
| Semaglutide / mo | $199/mo ($159 on a 12-month plan) | $79/mo (microdose tier, 12-month plan, compounded) |
| Tirzepatide / mo | $299/mo ($239 on a 12-month plan) | $139/mo (microdose tier, 12-month plan, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $948 |
| Tirzepatide / yr (modeled) | $3,588 | $1,668 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Yes | Yes |
| Rank on the board | #3 | #125 |
ShedRx (Shed)
87/100Where the value is
- Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
- Brand Zepbound and Wegovy available alongside the compounded line
- Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee
The tradeoffs
- The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Good Girl Rx
68/100Where the value is
- LegitScript certified
- Multiple formats — injectable, microdose, and ODT pills — for both semaglutide and tirzepatide
- Dispensed by licensed 503A or 503B pharmacies
The tradeoffs
- The advertised rates require twelve months paid up front; billed month to month the same products are $184 and $244, roughly 2.3 times as much
- Every plan is prepaid — the discount exists only on the 3-, 6- and 12-month terms
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.