Head-to-head · Cost-Efficiency Index
ShedRx (Shed) vs AMP Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ShedRx (Shed)
People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.
Visit ShedRx (Shed)AMP Health
Patients wanting oral semaglutide with coaching support.
Visit AMP HealthThe verdict
ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 66. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. AMP Health still earns a C — Patients wanting oral semaglutide with coaching support.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ShedRx (Shed) | AMP Health |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 66/100 |
| Semaglutide / mo | $199/mo ($159 on a 12-month plan) | $199/mo (compounded) |
| Tirzepatide / mo | $299/mo ($239 on a 12-month plan) | $309/mo (compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,388 |
| Tirzepatide / yr (modeled) | $3,588 | $3,708 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Yes | Yes |
| Rank on the board | #3 | #145 |
ShedRx (Shed)
87/100Where the value is
- Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
- Brand Zepbound and Wegovy available alongside the compounded line
- Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee
The tradeoffs
- The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
AMP Health
66/100Where the value is
- Semaglutide in both injectable and oral formats
- Tirzepatide available
- 30-day satisfaction guarantee
The tradeoffs
- $79/mo subscription fee on top of medication ($278–$388/mo total)
- No visible LegitScript or PCAB accreditation
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.