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Head-to-head · Cost-Efficiency Index

Sesame Care vs Measured

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B · #6

Sesame Care

People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost.

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VS
Grade C · #103

Measured

People who want coaching-forward metabolic care and the choice of compounded or brand-name GLP-1s.

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The verdict

Winner · Sesame CareGrade B vs C

Sesame Care takes it, leading the Cost-Efficiency Index 86 to 70. The widest real brand-name GLP-1 access on the board — a LegitScript- and BBB-recognized national marketplace running since 2018 that dispenses FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro and Rybelsus, not compounded copies. Measured still earns a CPeople who want coaching-forward metabolic care and the choice of compounded or brand-name GLP-1s.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Sesame Care.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

76
91

Price Transparency

82
86

Nationwide Access

92
24

Formulation Options

95
79

Clinical Oversight

89
88

Contract Flexibility

84
41

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecSesame CareMeasured
Cost-Efficiency Index86/10070/100
Semaglutide / mo$149/mo (brand)$119/mo (compounded)
Tirzepatide / moBrand (Zepbound)$219/mo (compounded)
Semaglutide / yr (modeled)$1,428
Tirzepatide / yr (modeled)$2,628
CoverageNationwideCoverage not published
Oral / sublingualYesNo
Brand-name accessYesYes
Rank on the board#6#103

Sesame Care

86/100

Where the value is

  • Widest brand-name formulary we list — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and oral Rybelsus, all FDA-approved rather than compounded
  • Established national marketplace operating since 2018, with LegitScript certification and BBB recognition
  • Wegovy pill starts around $149/mo, and oral routes are available for the needle-averse

The tradeoffs

  • Two-part cost — the medication price is separate from a platform subscription, so the all-in monthly runs above the $149 headline
  • A generalist telehealth marketplace, not a dedicated GLP-1 program
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Full Sesame Care review →

Measured

70/100

Where the value is

  • Membership includes 1:1 nutrition support and board-certified provider care
  • Both compounded (from $79/mo microdose, $119 semaglutide, $229 tirzepatide) and brand-name Wegovy/Zepbound
  • Insurance or cash-pay options for brand-name medications

The tradeoffs

  • The headline $79 'GLP-1 Microdose' is a promotional rate off a $99 list price, is filed by the provider under longevity rather than weight loss, and is not a labelled therapeutic dose of either molecule
  • Branded plans are a $49/mo membership with the medication billed separately at $149 to $449/mo
Visit Measured

Full Measured review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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