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Head-to-head · Cost-Efficiency Index

PreventiveMD vs NiceRx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #44

PreventiveMD

Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths.

Visit PreventiveMD
VS
Grade C · #50

NiceRx

Cost-first shoppers who want a clearly disclosed standing month-to-month rate rather than a prepay-gated one.

Visit NiceRx

The verdict

Winner · PreventiveMDGrade C vs C

PreventiveMD takes it, leading the Cost-Efficiency Index 77 to 76. PreventiveMD is a physician-guided telehealth platform for GLP-1 weight loss and peptide therapy, offering compounded semaglutide from $83/mo all-in and compounded tirzepatide from $97/mo all-in. NiceRx still earns a CCost-first shoppers who want a clearly disclosed standing month-to-month rate rather than a prepay-gated one.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs PreventiveMD.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

87
69

Price Transparency

78
94

Nationwide Access

66
78

Formulation Options

84
66

Clinical Oversight

82
86

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecPreventiveMDNiceRx
Cost-Efficiency Index77/10076/100
Semaglutide / mo$83/mo (as low as, term not published, all-in, compounded)$199/mo (all doses, compounded)
Tirzepatide / mo$97/mo (as low as, term not published, all-in, compounded)$299/mo (all doses, compounded)
Semaglutide / yr (modeled)$996$2,388
Tirzepatide / yr (modeled)$1,164$3,588
Coverage36 states46 states
Oral / sublingualNoNo
Brand-name accessYesCompounded only
Rank here#44#50

PreventiveMD

77/100

Where the value is

  • Compounded semaglutide from $83/mo and tirzepatide from $97/mo, billed as one all-in monthly price
  • Brand Wegovy, Zepbound, and Foundayo (oral GLP-1) available on the same platform
  • US-licensed provider reviews requests within 24 hours — no video visit required

The tradeoffs

  • Both figures are 'as low as' rates and the qualifying term is not published anywhere — the checkout is gated, so whether $97 is month-to-month or a multi-month prepay cannot be established before signing up
  • Brand-name routes are priced separately and do carry a fee: $49/mo membership plus medication from $149/mo for Foundayo and Wegovy, from $299/mo for Zepbound
Visit PreventiveMD

Full PreventiveMD review →

NiceRx

76/100

Where the value is

  • Explicitly discloses both the promotional first-month price and the real ongoing 'every month thereafter' rate on the same page, rather than only advertising the promo
  • Flat pricing across all doses, with the provider visit and shipping bundled into the price
  • Cancel-anytime billing with no long-term commitment structure found

The tradeoffs

  • Not available in Alaska, Mississippi, New Jersey, or Kansas
  • Compounded only — no FDA-approved brand option
Visit NiceRx

Full NiceRx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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