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Head-to-head · Cost-Efficiency Index

PrescribedRX vs VigorMeds

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #412

PrescribedRX

Shoppers who want flat, dose-independent pricing and are also interested in bundling TRT or hair loss treatment on the same platform.

Visit PrescribedRX
VS
Grade C · #416

VigorMeds

Cost-first shoppers who want a needle-free sublingual GLP-1 that's meaningfully cheaper than the injectable version, from named physicians.

Visit VigorMeds

The verdict

Too close to callGrade C vs C

PrescribedRX and VigorMeds tie on the Cost-Efficiency Index at 50/100, so neither wins outright on the numbers. For most shoppers we'd start with PrescribedRX (ranked #412, a hair above #416) — Shoppers who want flat, dose-independent pricing and are also interested in bundling TRT or hair loss treatment on the same platform. But VigorMeds is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs PrescribedRX.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

59
59

Price Transparency

46
30

Nationwide Access

24
24

Formulation Options

66
77

Clinical Oversight

80
78

Contract Flexibility

20
41

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecPrescribedRXVigorMeds
Cost-Efficiency Index50/10050/100
Semaglutide / mo$189/mo (all doses, prepay plan, compounded)$199/mo (starting dose, compounded)
Tirzepatide / mo$276/mo (all doses, prepay plan, compounded)$299/mo (starting dose, compounded)
Semaglutide / yr (modeled)$2,268$2,388
Tirzepatide / yr (modeled)$3,312$3,588
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyCompounded only
Rank here#412#416

PrescribedRX

50/100

Where the value is

  • Dose-flat pricing -- cost doesn't increase as you titrate up
  • Both compounded semaglutide and tirzepatide offered
  • LegitScript badge displayed

The tradeoffs

  • 3-month tirzepatide 'starting at' price is a $697 upfront prepay trap, not the real monthly rate
  • Confusing bundle pricing where the 'special offer' is actually pricier than the plain monthly plan
Visit PrescribedRX

Full PrescribedRX review →

VigorMeds

50/100

Where the value is

  • Both injectable and needle-free sublingual forms of semaglutide ($139/mo) and tirzepatide ($159/mo) — the sublingual tier is $60-$140/mo cheaper than the injectable tier
  • Named, credentialed clinicians reviewing cases: Dr. Anthony Kane MD, Dr. Claudia Mondragon MD, Dr. Kevin Kargman MD, Stephanie Kowatch MSN FNP-C
  • 'Pay upon medical approval' — no charge until a provider signs off on treatment, plus a 30-day satisfaction guarantee

The tradeoffs

  • The dedicated 'States We Serve' page names zero actual states in its crawlable content — only vague buckets like 'Coming soon' and 'Room to grow'
  • The FIRST100 promo code discounts whichever tier is chosen by $100 for the first month, so the price shown at signup is not the ongoing rate
Visit VigorMeds

Full VigorMeds review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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