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Head-to-head · Cost-Efficiency Index

Ondra Health vs Tuyo Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A− · #2

Ondra Health

Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.

Visit Ondra Health
VS
Grade C · #120

Tuyo Health

Shoppers wanting low-cost compounded glp-1 on an all-inclusive plan.

Visit Tuyo Health

The verdict

Winner · Ondra HealthGrade A− vs C

Ondra Health takes it, leading the Cost-Efficiency Index 90 to 69. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Tuyo Health still earns a CShoppers wanting low-cost compounded glp-1 on an all-inclusive plan.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

94
85

Price Transparency

88
94

Nationwide Access

96
24

Formulation Options

86
79

Clinical Oversight

88
76

Contract Flexibility

88
41

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecOndra HealthTuyo Health
Cost-Efficiency Index90/10069/100
Semaglutide / mo$93/mo$155/mo
Tirzepatide / mo$166/mo$279/mo
Semaglutide / yr (modeled)$1,116$1,860
Tirzepatide / yr (modeled)$1,992$3,348
CoverageAll 50 statesCoverage not published
Oral / sublingualNoNo
Brand-name accessYesYes
Rank on the board#2#120

Ondra Health

90/100

Where the value is

  • Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
  • Available in all 50 states with both molecules published for clean cost modeling
  • LegitScript-certified, and offers FDA-approved brand-name access alongside compounded

The tradeoffs

  • A newer, lower-profile operator without CoreAge's long flat-price track record
  • No oral/sublingual route
Visit Ondra Health

Full Ondra Health review →

Tuyo Health

69/100

Where the value is

  • Low starting price of 155 dollars per month for compounded semaglutide, all-inclusive
  • Offers both compounded and brand-name Wegovy and Zepbound, with an insurance option
  • Free same-week shipping, complimentary consults and periodic lab work included

The tradeoffs

  • Service-area states not published
  • No specific compounding pharmacy named on the site
Visit Tuyo Health

Full Tuyo Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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