Head-to-head · Cost-Efficiency Index
Ondra Health vs Southern Vitality and Weight Loss
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ondra Health
Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.
Visit Ondra HealthSouthern Vitality and Weight Loss
Cost-sensitive shoppers wanting cheap compounded GLP-1 from a provider that names its pharmacies.
Visit Southern Vitality and Weight LossThe verdict
Ondra Health takes it, leading the Cost-Efficiency Index 90 to 62. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Southern Vitality and Weight Loss still earns a C — Cost-sensitive shoppers wanting cheap compounded GLP-1 from a provider that names its pharmacies.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ondra Health | Southern Vitality and Weight Loss |
|---|---|---|
| Cost-Efficiency Index | 90/100 | 62/100 |
| Semaglutide / mo | $93/mo | $199/mo (compounded) |
| Tirzepatide / mo | $166/mo | $299/mo (compounded) |
| Semaglutide / yr (modeled) | $1,116 | $2,388 |
| Tirzepatide / yr (modeled) | $1,992 | $3,588 |
| Coverage | All 50 states | 1 state |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank on the board | #2 | #215 |
Ondra Health
90/100Where the value is
- Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
- Available in all 50 states with both molecules published for clean cost modeling
- LegitScript-certified, and offers FDA-approved brand-name access alongside compounded
The tradeoffs
- A newer, lower-profile operator without CoreAge's long flat-price track record
- No oral/sublingual route
Southern Vitality and Weight Loss
62/100Where the value is
- Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
- Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
- Free telehealth consult and free shipping; no membership or hidden fees
The tradeoffs
- This is one physical clinic in Valdosta, Georgia, not a national telehealth service — nothing here is available to a reader outside Georgia
- The advertised 'as low as $99/month' is a semaglutide three-month starter pack ($299 paid up front), not a tirzepatide rate and not a monthly one
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.