Head-to-head · Cost-Efficiency Index
Ondra Health vs RxPepsDirect
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ondra Health
Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.
Visit Ondra HealthRxPepsDirect
Cost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.
Visit RxPepsDirectThe verdict
Ondra Health takes it, leading the Cost-Efficiency Index 90 to 60. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. RxPepsDirect still earns a C — Cost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ondra Health | RxPepsDirect |
|---|---|---|
| Cost-Efficiency Index | 90/100 | 60/100 |
| Semaglutide / mo | $93/mo | $79/mo (starting dose, visit fee and shipping included, compounded) |
| Tirzepatide / mo | $166/mo | $99/mo (starting dose, visit fee and shipping included, compounded) |
| Semaglutide / yr (modeled) | $1,116 | $948 |
| Tirzepatide / yr (modeled) | $1,992 | $1,188 |
| Coverage | All 50 states | 28 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank on the board | #2 | #239 |
Ondra Health
90/100Where the value is
- Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
- Available in all 50 states with both molecules published for clean cost modeling
- LegitScript-certified, and offers FDA-approved brand-name access alongside compounded
The tradeoffs
- A newer, lower-profile operator without CoreAge's long flat-price track record
- No oral/sublingual route
RxPepsDirect
60/100Where the value is
- Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
- No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
- Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas Board #34829
The tradeoffs
- The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
- Higher doses need more than one vial a month and the site publishes no price for the dose you titrate up to, so the figure above is a floor
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.