Head-to-head · Cost-Efficiency Index
NuDay Rx vs Youth & Soul
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
NuDay Rx
Shoppers who want both compounded and brand-name GLP-1 options with a named pharmacy on one platform.
Visit NuDay RxYouth & Soul
Shoppers who want a named compounding pharmacy and nationwide shipping with both compounded and branded GLP-1 options in one place.
Visit Youth & SoulThe verdict
NuDay Rx and Youth & Soul tie on the Cost-Efficiency Index at 61/100, so neither wins outright on the numbers. For most shoppers we'd start with NuDay Rx (ranked #232, a hair above #239) — Shoppers who want both compounded and brand-name GLP-1 options with a named pharmacy on one platform. But Youth & Soul is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs NuDay Rx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | NuDay Rx | Youth & Soul |
|---|---|---|
| Cost-Efficiency Index | 61/100 | 61/100 |
| Semaglutide / mo | $249/mo (compounded) | $149/mo (compounded) |
| Tirzepatide / mo | $329/mo (compounded) | $149/mo (compounded) |
| Semaglutide / yr (modeled) | $2,988 | $1,788 |
| Tirzepatide / yr (modeled) | $3,948 | $1,788 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Yes |
| Rank here | #232 | #239 |
NuDay Rx
61/100Where the value is
- Named compounding pharmacy (Belmar Pharmacy) and named prescriber network (Beluga Health) — both independently verifiable
- LegitScript verification badge displayed on-site
- Both injectable and oral-tablet forms available for semaglutide and tirzepatide, plus a full brand-name menu on the same account
The tradeoffs
- Compounded semaglutide ($249) and tirzepatide ($329) are priced above several budget competitors in this comparison set
- Oral tirzepatide tablets ($399/mo) cost more than the injectable compound form ($329/mo) — a naive assumption that oral is cheaper or equivalent would be wrong here
Youth & Soul
61/100Where the value is
- Named, verifiable compounding pharmacy partner (Procompounding Pharmacy) plus a named fulfillment partner (The Pharmacy Hub)
- Claims all-50-state shipping
- LegitScript seal displayed
The tradeoffs
- Primary marketing domain (youthandsoul.com) simply redirects to a differently-spelled live site, which could confuse shoppers
- 'From $149/mo' headline price isn't broken out by exact dose, and the referenced 'Level 1-3' tier structure isn't fully published
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.