Head-to-head · Cost-Efficiency Index
Nouri vs Zeuss
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Nouri
Shoppers who want a flat any-dose price and are willing to prepay 6 months to get the lowest rate.
Visit NouriZeuss
Patients already stable on a maintenance GLP-1 dose who want to pay per fill instead of a subscription.
Visit ZeussThe verdict
Nouri takes it, leading the Cost-Efficiency Index 64 to 63. Nouri is a 50-state GLP-1 telehealth provider prescribing through Wasef Health, PC (Dr. Michael Wasef, MD) and dispensing via 503A-licensed F&F Pharmacies dba Jungle Jim's Pharmacy (Fairfield, OH). Zeuss still earns a C — Patients already stable on a maintenance GLP-1 dose who want to pay per fill instead of a subscription.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Nouri.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Nouri | Zeuss |
|---|---|---|
| Cost-Efficiency Index | 64/100 | 63/100 |
| Semaglutide / mo | $175/mo (all doses, prepay plan, compounded) | $125/mo (starting dose, compounded) |
| Tirzepatide / mo | $225/mo (all doses, prepay plan, compounded) | $175/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $2,100 | $1,500 |
| Tirzepatide / yr (modeled) | $2,700 | $2,100 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #183 | #186 |
Nouri
64/100Where the value is
- 'Any dose, same price' means no dose-escalation surcharge — unlike most compounded-GLP-1 competitors
- Names a real, licensed 503A compounding pharmacy (F&F Pharmacies dba Jungle Jim's Pharmacy, Fairfield, OH) and a named prescribing physician (Dr. Michael Wasef, MD)
- Bundles nutrition planning, movement planning, and concierge care into every tier at no extra charge, per the site's own claim
The tradeoffs
- The advertised 'starting at' headline price ($120 semaglutide / $175 tirzepatide) is the 6-month PREPAY rate only — the true month-to-month price is 46% and 29% higher respectively ($175 / $225)
- The 30-day money-back guarantee explicitly excludes the monthly (no-prepay) plan
Zeuss
63/100Where the value is
- Genuinely no-subscription billing confirmed in its own FAQ ('no recurring charges or automatic refills') — patients pay per order, not a locked recurring plan
- LegitScript certified, with the badge and verification link displayed on the homepage
- States it 'partners exclusively with 503A and 503B state-licensed compounding pharmacies'
The tradeoffs
- Both $125 and $175 are 'starting at' prices with no disclosed dose (mg) or confirmation the price holds at higher/titrated doses
- No compounding pharmacy is named, only 'licensed partner pharmacy'
Regulatory note: the FDA issued a warning letter to Zeuss LLC dba Zeuss in February 2026. We still list and link to Zeuss; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.