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Head-to-head · Cost-Efficiency Index

MDLive vs Trimrose

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #410

MDLive

Cost-first shoppers who want not a fit for GLP-1 price shopping -- best suited to patients who already have MDLIVE access for general primary care.

Visit MDLive
VS
Grade C · #415

Trimrose

Shoppers who want a named medical director and pharmacy partners plus the option to step up to branded GLP-1s on the same platform.

Visit Trimrose

The verdict

Too close to callGrade C vs C

MDLive and Trimrose tie on the Cost-Efficiency Index at 50/100, so neither wins outright on the numbers. For most shoppers we'd start with MDLive (ranked #410, a hair above #415) — Cost-first shoppers who want not a fit for GLP-1 price shopping -- best suited to patients who already have MDLIVE access for general primary care. But Trimrose is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs MDLive.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
49

Price Transparency

54
30

Nationwide Access

24
24

Formulation Options

53
90

Clinical Oversight

85
69

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecMDLiveTrimrose
Cost-Efficiency Index50/10050/100
Semaglutide / moNot disclosed$269/mo (starting dose, compounded)
Tirzepatide / moNot disclosed$359/mo (starting dose, compounded)
Semaglutide / yr (modeled)$3,228
Tirzepatide / yr (modeled)$4,308
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessYesYes
Rank here#410#415

MDLive

50/100

Where the value is

  • Backed by a major, established telehealth/insurance parent (Evernorth/Cigna)
  • Access to FDA-approved branded anti-obesity medications, not unregulated compounds
  • Broad general primary-care telehealth infrastructure

The tradeoffs

  • No dedicated GLP-1 or weight-loss program -- medications are folded into general primary care visits only
  • No medication-specific pricing published anywhere
Visit MDLive

Full MDLive review →

Trimrose

50/100

Where the value is

  • LegitScript-verified with a displayed seal
  • Named medical directors with public NPI numbers, unusual transparency versus peers
  • Four named, identifiable compounding pharmacy partners

The tradeoffs

  • All prices are 'starting at' floors -- actual monthly cost rises with dose and is not fully disclosed upfront
  • A separate $60 first-visit fee is layered on top of the monthly medication price
Visit Trimrose

Full Trimrose review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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