Head-to-head · Cost-Efficiency Index
Lean Meds vs Curex
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Lean Meds
Cost-first shoppers who want a genuinely flat all-dose price and named pharmacies, and who will read the $49 headline as the annual plan it is.
Visit Lean MedsCurex
People who want a low-cost first month, an oral option, and a verified pharmacy nationwide, and don't need a dose-by-dose price table before signing up.
Visit CurexThe verdict
Lean Meds takes it, leading the Cost-Efficiency Index 84 to 81. Lean Meds charges $79 a month for compounded semaglutide and $109 for tirzepatide, flat at every dose, names the four pharmacies that fill the prescriptions, and advertises a $49 figure that is really its twelve-month rate. Curex still earns a B− — People who want a low-cost first month, an oral option, and a verified pharmacy nationwide, and don't need a dose-by-dose price table before signing up.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Lean Meds.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Lean Meds | Curex |
|---|---|---|
| Cost-Efficiency Index | 84/100 | 81/100 |
| Semaglutide / mo | $79/mo month-to-month, flat at every dose (the advertised $49 is the 12-month plan) | $199/mo Starting (first month $49) |
| Tirzepatide / mo | $109/mo month-to-month, flat at every dose (the advertised $95 is the 12-month plan) | $199/mo Starting (first month $149) |
| Semaglutide / yr (modeled) | $948 | $2,388 |
| Tirzepatide / yr (modeled) | $1,308 | $2,388 |
| Coverage | All 50 states | All 50 states (California: oral tablet only, no injectable) |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #21 | #27 |
Lean Meds
84/100Where the value is
- A flat rate at every dose on both molecules, stated as such, so the price does not climb as a provider titrates
- Names all four pharmacies in its network with addresses, phone numbers and websites, and states the 503A designation in the footer of every page
- The full four-rung ladder for each molecule is printed on one page, so a reader can see what a commitment actually saves
The tradeoffs
- The homepage sells "Starting at $49/mo — same price every month, first order and every order after"; $49 is the twelve-month semaglutide plan and the month-to-month rate is $79
- A homepage chip reads "No auto rebill" while the terms say the payment method is automatically charged at recurring intervals until you cancel
Curex
81/100Where the value is
- Discounted first month well below the ongoing rate — $49 for semaglutide, $149 for tirzepatide
- Nationwide enrollment (all 50 states) plus an oral/sublingual route as an alternative to injections
- 365-day money-back guarantee and a full refund if never prescribed
The tradeoffs
- The '$199/mo' figure is labeled 'Starting,' not flat — no dose-by-dose price table is published, so the real cost at a higher maintenance dose is unverified
- California residents cannot get the injectable route at all — oral tablets only, despite the 'all 50 states' enrollment claim
Regulatory note: the FDA issued a warning letter to Curex in September 2025. We still list and link to Curex; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.