Head-to-head · Cost-Efficiency Index
Invyncible vs June Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Invyncible
Cost-first shoppers who want compounded GLP-1 combo programs (with B12/glycine) alongside brand Wegovy/Zepbound on one platform.
Visit InvyncibleJune Health
Cost-first shoppers who want not clearly differentiated from other entry-level GLP-1 telehealth storefronts; caution warranted given its newness.
Visit June HealthThe verdict
Invyncible and June Health tie on the Cost-Efficiency Index at 59/100, so neither wins outright on the numbers. For most shoppers we'd start with Invyncible (ranked #272, a hair above #273) — Cost-first shoppers who want compounded GLP-1 combo programs (with B12/glycine) alongside brand Wegovy/Zepbound on one platform. But June Health is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Invyncible.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Invyncible | June Health |
|---|---|---|
| Cost-Efficiency Index | 59/100 | 59/100 |
| Semaglutide / mo | $149/mo (0.45 mg dose, compounded with glycine + B12) | $199/mo (compounded) |
| Tirzepatide / mo | $180/mo (2.5 mg weekly, 4-week program, compounded) | $199/mo (compounded) |
| Semaglutide / yr (modeled) | $1,788 | $2,388 |
| Tirzepatide / yr (modeled) | $2,160 | $2,388 |
| Coverage | 46 states plus DC | Coverage not published |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Yes | Compounded only |
| Rank here | #272 | #273 |
Invyncible
59/100Where the value is
- Publishes real itemized dollar prices for eight separate combo programs plus two brand options directly on the site, no signup required, with the mg vial size named in every dose option
- Sells FDA-approved brand Wegovy ($1,750/mo) and Zepbound ($1,540/mo) alongside compounded options
- Names all six compounding pharmacies with street addresses and phone numbers and lets the patient choose which one fills the prescription
The tradeoffs
- Every listed price is shown as a discount off a much higher struck-through 'list' price, and the page invites further negotiation — reads as permanent anchor pricing
- The entry figure is the smallest vial: plain compounded semaglutide runs $192.50, $262.50 and $350 across its three vial sizes, and the FAQ confirms cost rises with dose
June Health
59/100Where the value is
- Low advertised entry price ($199/mo)
- Claims licensed providers in all 50 states
- Real legal/policy pages present in the footer despite being a new site
The tradeoffs
- Very new operation -- domain reportedly registered only in May 2026
- No LegitScript badge or certification mention found anywhere on the site
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.