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Head-to-head · Cost-Efficiency Index

Invigor Medical vs Amazon One Medical

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #8

Invigor Medical

Value shoppers who want competitive pricing on both molecules plus a wider wellness/hormone program on one account.

Visit Invigor Medical
VS
Grade C · #42

Amazon One Medical

Cost-first shoppers who want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings.

Visit Amazon One Medical

The verdict

Winner · Invigor MedicalGrade B+ vs C

Invigor Medical takes it, leading the Cost-Efficiency Index 88 to 78. Solid mid-market cost on both molecules from an established operator — good value if you also want a broader metabolic and hormone catalog. Amazon One Medical still earns a CCost-first shoppers who want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Invigor Medical.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
81

Price Transparency

84
86

Nationwide Access

78
86

Formulation Options

82
58

Clinical Oversight

86
91

Contract Flexibility

87
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecInvigor MedicalAmazon One Medical
Cost-Efficiency Index88/10078/100
Semaglutide / mo$199/moNot disclosed
Tirzepatide / mo$339/moNot disclosed
Semaglutide / yr (modeled)$2,388
Tirzepatide / yr (modeled)$4,068
CoverageNot disclosedAll 50 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank on the board#8#42

Invigor Medical

88/100

Where the value is

  • Competitive mid-market pricing on both semaglutide and tirzepatide
  • Long-running operator with a broad catalog that can consolidate spend
  • Both molecules published up front for easy cost modeling

The tradeoffs

  • Does not publish an explicit states-served list, so access is a variable in the model
  • Compounded only
Visit Invigor Medical

Full Invigor Medical review →

Amazon One Medical

78/100

Where the value is

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand

The tradeoffs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
Visit Amazon One Medical

Full Amazon One Medical review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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