Head-to-head · Cost-Efficiency Index
Human+ vs Lean Rx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Human+
Cost-first shoppers who want pharmacy-wholesale pricing via a flat membership, in any state.
Visit Human+Lean Rx
Shoppers who don't need transparency on credentials before comparing headline prices.
Visit Lean RxThe verdict
Human+ and Lean Rx tie on the Cost-Efficiency Index at 58/100, so neither wins outright on the numbers. For most shoppers we'd start with Human+ (ranked #287, a hair above #288) — Cost-first shoppers who want pharmacy-wholesale pricing via a flat membership, in any state. But Lean Rx is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Human+.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Human+ | Lean Rx |
|---|---|---|
| Cost-Efficiency Index | 58/100 | 58/100 |
| Semaglutide / mo | Not disclosed | $266/mo (starting dose, compounded) |
| Tirzepatide / mo | Not disclosed | $399/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | — | $3,192 |
| Tirzepatide / yr (modeled) | — | $4,788 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #287 | #288 |
Human+
58/100Where the value is
- Cost-transparent model: a flat monthly membership with prescriptions billed at pharmacy-wholesale cost instead of marked up
- Available via telehealth in all 50 states
- Filled by US 503A compounding pharmacies and reviewed by board-certified US-licensed clinicians
The tradeoffs
- Specific GLP-1 medications and pricing are not published — you only see them after starting the intake
- Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
Lean Rx
58/100Where the value is
- Offers both semaglutide and tirzepatide
- Simple, low headline starting prices
- Straightforward telehealth consultation flow described
The tradeoffs
- No LegitScript certification displayed anywhere on the site
- No named medical director or compounding pharmacy partner
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.