Head-to-head · Cost-Efficiency Index
Eden vs Synergy Rx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Eden
People who will trade a higher sticker price for verified nationwide access and stronger clinical oversight.
Visit EdenSynergy Rx
People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by enquiry.
Visit Synergy RxThe verdict
Eden takes it, leading the Cost-Efficiency Index 86 to 71. You pay a premium per month, but you buy back certainty: all-50 access and high-disclosure clinical oversight that hold their value. Synergy Rx still earns a C — People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by enquiry.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Eden.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Eden | Synergy Rx |
|---|---|---|
| Cost-Efficiency Index | 86/100 | 71/100 |
| Semaglutide / mo | $239/mo | From $199/mo |
| Tirzepatide / mo | $349/mo | From $349/mo |
| Semaglutide / yr (modeled) | $2,868 | $2,388 |
| Tirzepatide / yr (modeled) | $4,188 | $4,188 |
| Coverage | All 50 states | Not disclosed |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank on the board | #8 | #31 |
Eden
86/100Where the value is
- High transparency — clear supply-chain and clinician disclosure lowers hidden-cost risk
- Nationwide availability with both molecules disclosed
- Strong clinical oversight adds value beyond the raw price
The tradeoffs
- Premium per-month cost drags its normalized value score
- Compounded only — no brand-name access
Synergy Rx
71/100Where the value is
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate, not compounded only
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- A $100 welcome credit applied at checkout, and FSA/HSA eligible
The tradeoffs
- Publishes no GLP-1 price anywhere on its own site, so total cost cannot be modelled before an enquiry
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.