Head-to-head · Cost-Efficiency Index
Curve vs Peptivo
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Curve
Cost-first shoppers who want legitScript-certified compounded GLP-1 at flat per-dose pricing.
Visit CurvePeptivo
Shoppers who value verifiable named pharmacy and medical-leadership credentials, willing to complete an intake quiz to see final pricing.
Visit PeptivoThe verdict
Curve and Peptivo tie on the Cost-Efficiency Index at 63/100, so neither wins outright on the numbers. For most shoppers we'd start with Curve (ranked #192, a hair above #199) — Cost-first shoppers who want legitScript-certified compounded GLP-1 at flat per-dose pricing. But Peptivo is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Curve.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Curve | Peptivo |
|---|---|---|
| Cost-Efficiency Index | 63/100 | 63/100 |
| Semaglutide / mo | $175/mo (compounded) | $169/mo (compounded) |
| Tirzepatide / mo | $225/mo (compounded) | $249/mo (compounded) |
| Semaglutide / yr (modeled) | $2,100 | $2,028 |
| Tirzepatide / yr (modeled) | $2,700 | $2,988 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #192 | #199 |
Curve
63/100Where the value is
- Offers both compounded semaglutide and tirzepatide, with every dose priced the same so cost does not rise as you titrate up.
- LegitScript-certified (seal #51079066) and names both its 503A compounding pharmacy, VialsRx, and its provider network, Beluga Health.
- Transparent tiered pricing with a real month-to-month option; consultation, medication, and free expedited shipping included, no membership.
The tradeoffs
- Very new (2026 launch) with a thin track record; the site still shows a Webflow template credit and a leftover Cora reference in its Terms.
- The cheapest headline rates ($99 semaglutide / $135 tirzepatide) require a 12-month prepay; true month-to-month is $175 and $225.
Peptivo
63/100Where the value is
- Four named, verifiable compounding pharmacy partners across multiple states
- Named Chief Medical Innovation Officer (MD) and VP of Pharmacy Operations, plus a physician advisory board
- Ships to all 50 states
The tradeoffs
- Exact GLP-1 pricing gated behind an intake quiz, not shown as a static table
- Company's own sibling NAD+ products use a first-month-then-higher pricing structure, raising unconfirmed suspicion the GLP-1 pricing may work the same way
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.