Head-to-head · Cost-Efficiency Index
Belle Health vs Invyncible
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Belle Health
Cost-first shoppers who want flat-rate compounded GLP-1 pricing that doesn't rise as the dose increases.
Visit Belle HealthInvyncible
Cost-first shoppers who want compounded GLP-1 combo programs (with B12/glycine) alongside brand Wegovy/Zepbound on one platform.
Visit InvyncibleThe verdict
Belle Health and Invyncible tie on the Cost-Efficiency Index at 59/100, so neither wins outright on the numbers. For most shoppers we'd start with Belle Health (ranked #268, a hair above #272) — Cost-first shoppers who want flat-rate compounded GLP-1 pricing that doesn't rise as the dose increases. But Invyncible is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Belle Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Belle Health | Invyncible |
|---|---|---|
| Cost-Efficiency Index | 59/100 | 59/100 |
| Semaglutide / mo | Not disclosed | $149/mo (0.45 mg dose, compounded with glycine + B12) |
| Tirzepatide / mo | Not disclosed | $180/mo (2.5 mg weekly, 4-week program, compounded) |
| Semaglutide / yr (modeled) | — | $1,788 |
| Tirzepatide / yr (modeled) | — | $2,160 |
| Coverage | All 50 states | 46 states plus DC |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Yes |
| Rank here | #268 | #272 |
Belle Health
59/100Where the value is
- Flat-rate pricing explicitly stated not to increase at higher doses
- Five named compounding pharmacy partners disclosed across its pages (BPI Labs, Hallandale Health, Boudreaux's, VialsRx, and others)
- 2-day shipping stated as included in the price, with no separate shipping line item found
The tradeoffs
- Tirzepatide price is inconsistent across Belle's own pages — $175/mo, $199/mo, and a $219 anchor all appear on different pages with no explanation
- No state-coverage list found on any page read, despite an FAQ item promising one
Regulatory note: the FDA issued a warning letter to Belle Health LLC dba Belle in February 2026. We still list and link to Belle Health; you should know the letter is on the public record before you decide.
Invyncible
59/100Where the value is
- Publishes real itemized dollar prices for eight separate combo programs plus two brand options directly on the site, no signup required, with the mg vial size named in every dose option
- Sells FDA-approved brand Wegovy ($1,750/mo) and Zepbound ($1,540/mo) alongside compounded options
- Names all six compounding pharmacies with street addresses and phone numbers and lets the patient choose which one fills the prescription
The tradeoffs
- Every listed price is shown as a discount off a much higher struck-through 'list' price, and the page invites further negotiation — reads as permanent anchor pricing
- The entry figure is the smallest vial: plain compounded semaglutide runs $192.50, $262.50 and $350 across its three vial sizes, and the FAQ confirms cost rises with dose
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.