Head-to-head · Cost-Efficiency Index
Belle Health vs CLYR Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Belle Health
Cost-first shoppers who want flat-rate compounded GLP-1 pricing that doesn't rise as the dose increases.
Visit Belle HealthCLYR Health
Shoppers comparing tirzepatide options who account for the post-first-month price increase rather than anchoring on the $149 headline.
Visit CLYR HealthThe verdict
Belle Health and CLYR Health tie on the Cost-Efficiency Index at 59/100, so neither wins outright on the numbers. For most shoppers we'd start with Belle Health (ranked #268, a hair above #271) — Cost-first shoppers who want flat-rate compounded GLP-1 pricing that doesn't rise as the dose increases. But CLYR Health is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Belle Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Belle Health | CLYR Health |
|---|---|---|
| Cost-Efficiency Index | 59/100 | 59/100 |
| Semaglutide / mo | Not disclosed | $169/mo (compounded) |
| Tirzepatide / mo | Not disclosed | $199/mo (compounded) |
| Semaglutide / yr (modeled) | — | $2,028 |
| Tirzepatide / yr (modeled) | — | $2,388 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #268 | #271 |
Belle Health
59/100Where the value is
- Flat-rate pricing explicitly stated not to increase at higher doses
- Five named compounding pharmacy partners disclosed across its pages (BPI Labs, Hallandale Health, Boudreaux's, VialsRx, and others)
- 2-day shipping stated as included in the price, with no separate shipping line item found
The tradeoffs
- Tirzepatide price is inconsistent across Belle's own pages — $175/mo, $199/mo, and a $219 anchor all appear on different pages with no explanation
- No state-coverage list found on any page read, despite an FAQ item promising one
Regulatory note: the FDA issued a warning letter to Belle Health LLC dba Belle in February 2026. We still list and link to Belle Health; you should know the letter is on the public record before you decide.
CLYR Health
59/100Where the value is
- LegitScript Certified badge displayed
- Named prescribing medical group (MD Integrations, PC) disclosed in Terms of Service
- 503A-licensed compounding pharmacy referenced
The tradeoffs
- Tirzepatide headline price ($149) is an explicit first-month-only rate -- real ongoing cost is $199/month
- Inconsistent states-served claims ('all 50 states' vs. 'ships to 47 states') on the same site
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.