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Head-to-head · Cost-Efficiency Index

Strut Health vs Semaglutide Online

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #4

Strut Health

Anyone optimising total monthly outlay who will keep an auto-refill running, and anyone whose real objection is the needle.

Visit Strut Health
VS
Grade B− · #32

Semaglutide Online

Cost-first shoppers who want legitScript GLP-1 nationwide ex. AL; compounded sema $199 or tirz $299/mo all-in; financing from $79/mo.

Visit Semaglutide Online

The verdict

Winner · Strut HealthGrade B+ vs B−

Strut Health takes it, leading the Cost-Efficiency Index 87 to 82. The lowest true entry cost on this board — $99/month sublingual semaglutide — and the only place selling the same molecule as a lozenge or an injection at one price. Semaglutide Online still earns a B−Cost-first shoppers who want legitScript GLP-1 nationwide ex. AL; compounded sema $199 or tirz $299/mo all-in; financing from $79/mo.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Strut Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

92
78

Price Transparency

84
94

Nationwide Access

90
86

Formulation Options

95
90

Clinical Oversight

68
81

Contract Flexibility

92
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecStrut HealthSemaglutide Online
Cost-Efficiency Index87/10082/100
Semaglutide / moFrom $99/mo sublingual, $149/mo injectable$199/mo (all doses, compounded)
Tirzepatide / moFrom $199/mo either route$299/mo (all doses, compounded)
Semaglutide / yr (modeled)$1,188$2,388
Tirzepatide / yr (modeled)$2,388$3,588
Coverage49 states (not Arkansas)All 50 states
Oral / sublingualYesYes
Brand-name accessCompounded onlyYes
Rank on the board#4#32

Strut Health

87/100

Where the value is

  • Cheapest disclosed monthly cost here at $99/mo for sublingual semaglutide; tirzepatide $199 either route
  • Sublingual lozenges for both molecules at the same price as the injection
  • Free physician visit, free shipping and free follow-up care included rather than billed separately

The tradeoffs

  • The $99 and $149 headline figures require auto-refill — a one-off order costs more, so the true cost depends on staying subscribed
  • Asynchronous by design: their FAQ notes some states need no phone consultation, so you may never speak to the prescriber
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Full Strut Health review →

Semaglutide Online

82/100

Where the value is

  • LegitScript certified — passes accreditation standards recognized by Google and Visa for online telehealth
  • Compounded all-in pricing: semaglutide $199/mo and tirzepatide $299/mo includes medication, provider care, and shipping
  • Brand-name options (Wegovy pill, injectable sema, Zepbound) available for eligible patients, potentially $0-$25/mo with insurance

The tradeoffs

  • No labs or clinical monitoring disclosed — blood work requirements not mentioned anywhere on site
  • Leadership team and medical director not identified on site — no named prescribers or company founders published
Visit Semaglutide Online

Full Semaglutide Online review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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