Head-to-head · Cost-Efficiency Index
Sesame Care vs WeightRx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Sesame Care
People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost.
Visit Sesame CareWeightRx
Cost-first shoppers who want the lowest published tirzepatide figure, if you are willing to complete intake before you can read the plan terms.
Visit WeightRxThe verdict
Sesame Care takes it, leading the Cost-Efficiency Index 86 to 69. The widest real brand-name GLP-1 access on the board — a LegitScript- and BBB-recognized national marketplace running since 2018 that dispenses FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro and Rybelsus, not compounded copies. WeightRx still earns a C — Cost-first shoppers who want the lowest published tirzepatide figure, if you are willing to complete intake before you can read the plan terms.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Sesame Care.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Sesame Care | WeightRx |
|---|---|---|
| Cost-Efficiency Index | 86/100 | 69/100 |
| Semaglutide / mo | $149/mo (brand) | $250/mo (compounded) |
| Tirzepatide / mo | Brand (Zepbound) | $83/mo (term not published, compounded) |
| Semaglutide / yr (modeled) | — | $3,000 |
| Tirzepatide / yr (modeled) | — | $996 |
| Coverage | Nationwide | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank on the board | #6 | #122 |
Sesame Care
86/100Where the value is
- Widest brand-name formulary we list — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and oral Rybelsus, all FDA-approved rather than compounded
- Established national marketplace operating since 2018, with LegitScript certification and BBB recognition
- Wegovy pill starts around $149/mo, and oral routes are available for the needle-averse
The tradeoffs
- Two-part cost — the medication price is separate from a platform subscription, so the all-in monthly runs above the $149 headline
- A generalist telehealth marketplace, not a dedicated GLP-1 program
WeightRx
69/100Where the value is
- The tirzepatide figure is published up front, and it is genuinely low against the field
- Both molecules are offered
- No membership charge is advertised alongside the medication rate
The tradeoffs
- The $83 monthly rate is advertised as '$83/month ($997/year)', which is twelve months of it — no month-to-month rate is separately published, and the terms state that a rate is locked for its full term
- Both product pages linked from the homepage return 404, so the plan terms cannot be read before intake
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.