Head-to-head · Cost-Efficiency Index
Sesame Care vs Oak
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Sesame Care
People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost.
Visit Sesame CareOak
Dose-escalators. A flat per-dose price means titrating from 0.25mg to 2.4mg costs the same every month, so the twelve-month number you model on day one is the number you pay.
Visit OakThe verdict
Sesame Care takes it, leading the Cost-Efficiency Index 86 to 83. The widest real brand-name GLP-1 access on the board — a LegitScript- and BBB-recognized national marketplace running since 2018 that dispenses FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro and Rybelsus, not compounded copies. Oak still earns a B — Dose-escalators. A flat per-dose price means titrating from 0.25mg to 2.4mg costs the same every month, so the twelve-month number you model on day one is the number you pay.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Sesame Care.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Sesame Care | Oak |
|---|---|---|
| Cost-Efficiency Index | 86/100 | 83/100 |
| Semaglutide / mo | $149/mo (brand) | $119/mo (same price at every dose) |
| Tirzepatide / mo | Brand (Zepbound) | $185/mo (same price at every dose) |
| Semaglutide / yr (modeled) | — | $1,428 |
| Tirzepatide / yr (modeled) | — | $2,220 |
| Coverage | Nationwide | 45 states (list not published) |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Yes | Compounded only |
| Rank on the board | #6 | #18 |
Sesame Care
86/100Where the value is
- Widest brand-name formulary we list — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and oral Rybelsus, all FDA-approved rather than compounded
- Established national marketplace operating since 2018, with LegitScript certification and BBB recognition
- Wegovy pill starts around $149/mo, and oral routes are available for the needle-averse
The tradeoffs
- Two-part cost — the medication price is separate from a platform subscription, so the all-in monthly runs above the $149 headline
- A generalist telehealth marketplace, not a dedicated GLP-1 program
Oak
83/100Where the value is
- $119 semaglutide and $185 tirzepatide — both among the lowest published on this board, and published before the intake rather than after it
- "ONE PRICE · ALL DOSAGES · NO SUBSCRIPTIONS" — the price does not climb as your dose does, which is where most flat-looking programs quietly get expensive
- A non-injectable route as well as the two weekly injections: sublingual drops or tablets targeting the GLP-1 pathway
The tradeoffs
- It publishes three different prices for the same product: $119 in the homepage hero, $167 in the homepage comparison table and on /product, and $190 in the /weightloss comparison table
- The "$200 OFF — NEW PATIENT OFFER" and "SUMMER SALE — Save up to 60% vs. retail pricing" banners carry no terms, no code and no resulting price anywhere on the site
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.