Head-to-head · Cost-Efficiency Index
Ondra Health vs Youth & Soul
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ondra Health
Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.
Visit Ondra HealthYouth & Soul
Shoppers who want many treatment categories in one account and are willing to verify claims themselves.
Visit Youth & SoulThe verdict
Ondra Health takes it, leading the Cost-Efficiency Index 90 to 60. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Youth & Soul still earns a C — Shoppers who want many treatment categories in one account and are willing to verify claims themselves.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ondra Health | Youth & Soul |
|---|---|---|
| Cost-Efficiency Index | 90/100 | 60/100 |
| Semaglutide / mo | $93/mo | $149/mo (starting dose, compounded) |
| Tirzepatide / mo | $166/mo | $399/mo (compounded) |
| Semaglutide / yr (modeled) | $1,116 | $1,788 |
| Tirzepatide / yr (modeled) | $1,992 | $4,788 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank on the board | #2 | #245 |
Ondra Health
90/100Where the value is
- Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
- Available in all 50 states with both molecules published for clean cost modeling
- LegitScript-certified, and offers FDA-approved brand-name access alongside compounded
The tradeoffs
- A newer, lower-profile operator without CoreAge's long flat-price track record
- No oral/sublingual route
Youth & Soul
60/100Where the value is
- Three GLP-1 tiers priced openly, with the dose range and every included component listed per tier
- Full refund advertised if you are not approved
- Physician consultation, prescription and shipping stated as included in the plan price
The tradeoffs
- Describes its compounded medications as FDA-Approved Compounds, which is false: compounded drugs are not FDA-approved
- Presents scraped third-party comments as testimonials, several using Reddit usernames and some describing brand Wegovy or Mounjaro
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.