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Head-to-head · Cost-Efficiency Index

Ondra Health vs Wholesome Clinic

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A− · #2

Ondra Health

Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.

Visit Ondra Health
VS
Grade C · #85

Wholesome Clinic

Cost-first shoppers who want multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.

Visit Wholesome Clinic

The verdict

Winner · Ondra HealthGrade A− vs C

Ondra Health takes it, leading the Cost-Efficiency Index 90 to 72. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Wholesome Clinic still earns a CCost-first shoppers who want multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

94
75

Price Transparency

88
78

Nationwide Access

96
42

Formulation Options

86
90

Clinical Oversight

88
92

Contract Flexibility

88
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecOndra HealthWholesome Clinic
Cost-Efficiency Index90/10072/100
Semaglutide / mo$93/mo$149/mo (starting dose, compounded)
Tirzepatide / mo$166/mo$349/mo (starting dose, compounded)
Semaglutide / yr (modeled)$1,116$1,788
Tirzepatide / yr (modeled)$1,992$4,188
CoverageAll 50 states7 states
Oral / sublingualNoYes
Brand-name accessYesYes
Rank on the board#2#85

Ondra Health

90/100

Where the value is

  • Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
  • Available in all 50 states with both molecules published for clean cost modeling
  • LegitScript-certified, and offers FDA-approved brand-name access alongside compounded

The tradeoffs

  • A newer, lower-profile operator without CoreAge's long flat-price track record
  • No oral/sublingual route
Visit Ondra Health

Full Ondra Health review →

Wholesome Clinic

72/100

Where the value is

  • Publishes standing per-dose self-pay prices for compounded semaglutide and tirzepatide, oral and injectable
  • Compounded semaglutide from $109/mo (oral) or $149/mo (injectable); brand Wegovy/Zepbound offered when appropriate
  • Telehealth across seven states plus an in-person option at its Frisco, TX office

The tradeoffs

  • $149 initial evaluation and $75 follow-up visits are billed separately from medication
  • Filled through your 'preferred pharmacy' — no single named compounding pharmacy partner
Visit Wholesome Clinic

Full Wholesome Clinic review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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