Head-to-head · Cost-Efficiency Index
Ondra Health vs Vital Edge
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ondra Health
Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.
Visit Ondra HealthVital Edge
People who want transparent flat-fee GLP-1 pricing with oral and brand-name options.
Visit Vital EdgeThe verdict
Ondra Health takes it, leading the Cost-Efficiency Index 90 to 54. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Vital Edge still earns a C — People who want transparent flat-fee GLP-1 pricing with oral and brand-name options.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ondra Health | Vital Edge |
|---|---|---|
| Cost-Efficiency Index | 90/100 | 54/100 |
| Semaglutide / mo | $93/mo | $350/mo (compounded) |
| Tirzepatide / mo | $166/mo | $450/mo (compounded) |
| Semaglutide / yr (modeled) | $1,116 | $4,200 |
| Tirzepatide / yr (modeled) | $1,992 | $5,400 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Yes |
| Rank on the board | #2 | #328 |
Ondra Health
90/100Where the value is
- Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
- Available in all 50 states with both molecules published for clean cost modeling
- LegitScript-certified, and offers FDA-approved brand-name access alongside compounded
The tradeoffs
- A newer, lower-profile operator without CoreAge's long flat-price track record
- No oral/sublingual route
Vital Edge
54/100Where the value is
- Transparent flat monthly pricing published on-site — consult, medication, and shipping all included
- Broad menu: compounded semaglutide/tirzepatide, compounded oral capsules from $199/mo, plus brand-name Ozempic, Wegovy, Mounjaro and Rybelsus
- LegitScript-certified (seal #43281221)
The tradeoffs
- Compounded injectable pricing ($350 semaglutide / $450 tirzepatide) runs above the lowest-cost telehealth options
- No compounding pharmacy partner named on the site
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.