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Head-to-head · Cost-Efficiency Index

Ondra Health vs Medro

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A− · #2

Ondra Health

Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.

Visit Ondra Health
VS
Grade C · #159

Medro

Cost-first shoppers who want compounded or brand semaglutide/tirzepatide with transparent tiered pricing and no membership, all 50 states.

Visit Medro

The verdict

Winner · Ondra HealthGrade A− vs C

Ondra Health takes it, leading the Cost-Efficiency Index 90 to 65. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Medro still earns a CCost-first shoppers who want compounded or brand semaglutide/tirzepatide with transparent tiered pricing and no membership, all 50 states.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

94
56

Price Transparency

88
62

Nationwide Access

96
86

Formulation Options

86
79

Clinical Oversight

88
71

Contract Flexibility

88
33

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecOndra HealthMedro
Cost-Efficiency Index90/10065/100
Semaglutide / mo$93/mo$199/mo (compounded)
Tirzepatide / mo$166/mo$299/mo (compounded)
Semaglutide / yr (modeled)$1,116$2,388
Tirzepatide / yr (modeled)$1,992$3,588
CoverageAll 50 statesAll 50 states
Oral / sublingualNoNo
Brand-name accessYesYes
Rank on the board#2#159

Ondra Health

90/100

Where the value is

  • Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
  • Available in all 50 states with both molecules published for clean cost modeling
  • LegitScript-certified, and offers FDA-approved brand-name access alongside compounded

The tradeoffs

  • A newer, lower-profile operator without CoreAge's long flat-price track record
  • No oral/sublingual route
Visit Ondra Health

Full Ondra Health review →

Medro

65/100

Where the value is

  • Covers both compounded semaglutide and tirzepatide and can prescribe brand-name GLP-1s when clinically appropriate.
  • LegitScript-certified (seal #50716646), available in all 50 states, with tiered pricing shown before checkout.
  • No membership fee and free expedited shipping on all orders; online intake with no appointment required in many cases.

The tradeoffs

  • Does not name its compounding pharmacy or its clinical partner medical group, so the fulfillment chain is not verifiable.
  • Pricing is described as illustrative and may change by dose, pharmacy availability, and eligibility — final cost shows only at checkout.
Visit Medro

Full Medro review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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