Head-to-head · Cost-Efficiency Index
Ondra Health vs CLYR Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ondra Health
Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.
Visit Ondra HealthCLYR Health
Cost-first shoppers who want flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up.
Visit CLYR HealthThe verdict
Ondra Health takes it, leading the Cost-Efficiency Index 90 to 60. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. CLYR Health still earns a C — Cost-first shoppers who want flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ondra Health | CLYR Health |
|---|---|---|
| Cost-Efficiency Index | 90/100 | 60/100 |
| Semaglutide / mo | $93/mo | $229/mo (compounded) |
| Tirzepatide / mo | $166/mo | $249/mo (compounded) |
| Semaglutide / yr (modeled) | $1,116 | $2,748 |
| Tirzepatide / yr (modeled) | $1,992 | $2,988 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Yes |
| Rank on the board | #2 | #234 |
Ondra Health
90/100Where the value is
- Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
- Available in all 50 states with both molecules published for clean cost modeling
- LegitScript-certified, and offers FDA-approved brand-name access alongside compounded
The tradeoffs
- A newer, lower-profile operator without CoreAge's long flat-price track record
- No oral/sublingual route
CLYR Health
60/100Where the value is
- Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
- LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
- 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo
The tradeoffs
- State availability gated behind intake; not published on the marketing site
- Standing monthly rates ($229-249) run above the cheapest compounded competitors
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.