Head-to-head · Cost-Efficiency Index
Ondra Health vs Blue Sky MD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ondra Health
Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.
Visit Ondra HealthBlue Sky MD
Cost-first shoppers who want legitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching.
Visit Blue Sky MDThe verdict
Ondra Health takes it, leading the Cost-Efficiency Index 90 to 64. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Blue Sky MD still earns a C — Cost-first shoppers who want legitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ondra Health | Blue Sky MD |
|---|---|---|
| Cost-Efficiency Index | 90/100 | 64/100 |
| Semaglutide / mo | $93/mo | $160/mo (starting dose, compounded) |
| Tirzepatide / mo | $166/mo | $240/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $1,116 | $1,920 |
| Tirzepatide / yr (modeled) | $1,992 | $2,880 |
| Coverage | All 50 states | 1 state |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank on the board | #2 | #167 |
Ondra Health
90/100Where the value is
- Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
- Available in all 50 states with both molecules published for clean cost modeling
- LegitScript-certified, and offers FDA-approved brand-name access alongside compounded
The tradeoffs
- A newer, lower-profile operator without CoreAge's long flat-price track record
- No oral/sublingual route
Blue Sky MD
64/100Where the value is
- LegitScript certified and physician-led since 2008; one of the most established GLP-1 practices in the Southeast
- Compounded semaglutide from $40/week (~$160/month) and tirzepatide from $60/week (~$240/month) — well below brand-name cost
- Comprehensive program includes 1-on-1 wellness coaching, nutrition plans, hormone analysis, and a proprietary mobile app
The tradeoffs
- Geographic reach unclear — physical clinics in NC only; telehealth states beyond NC unconfirmed despite 'from virtually anywhere' claim
- Pricing quoted per-week ($40 sema / $60 tirz) rather than per-month; higher-dose pricing not disclosed
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.