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Head-to-head · Cost-Efficiency Index

Ondra Health vs Big Easy Weight Loss

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A− · #2

Ondra Health

Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.

Visit Ondra Health
VS
Grade B− · #30

Big Easy Weight Loss

Cost-first shoppers who want budget shoppers wanting low-cost compounded glp-1 nationwide.

Visit Big Easy Weight Loss

The verdict

Winner · Ondra HealthGrade A− vs B−

Ondra Health takes it, leading the Cost-Efficiency Index 90 to 82. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Big Easy Weight Loss still earns a B−Cost-first shoppers who want budget shoppers wanting low-cost compounded glp-1 nationwide.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

94
90

Price Transparency

88
97

Nationwide Access

96
86

Formulation Options

86
66

Clinical Oversight

88
78

Contract Flexibility

88
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecOndra HealthBig Easy Weight Loss
Cost-Efficiency Index90/10082/100
Semaglutide / mo$93/mo$133/mo (all doses, compounded)
Tirzepatide / mo$166/mo$166/mo (all doses, compounded)
Semaglutide / yr (modeled)$1,116$1,596
Tirzepatide / yr (modeled)$1,992$1,992
CoverageAll 50 statesAll 50 states
Oral / sublingualNoNo
Brand-name accessYesCompounded only
Rank on the board#2#30

Ondra Health

90/100

Where the value is

  • Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
  • Available in all 50 states with both molecules published for clean cost modeling
  • LegitScript-certified, and offers FDA-approved brand-name access alongside compounded

The tradeoffs

  • A newer, lower-profile operator without CoreAge's long flat-price track record
  • No oral/sublingual route
Visit Ondra Health

Full Ondra Health review →

Big Easy Weight Loss

82/100

Where the value is

  • Low pricing: about 133 dollars per month for semaglutide, 166 for tirzepatide
  • Site states it serves all 50 states with a 2 to 3 day pharmacy turnaround
  • Names its partner compounding pharmacies and a Chief Medical Officer

The tradeoffs

  • Priced as 10 to 12-week packages rather than a simple monthly fee
  • New-patient pricing is promotional and may rise on renewal
Visit Big Easy Weight Loss

Full Big Easy Weight Loss review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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