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Head-to-head · Cost-Efficiency Index

Invigor Medical vs Wholesome Clinic

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #8

Invigor Medical

Value shoppers who want competitive pricing on both molecules plus a wider wellness/hormone program on one account.

Visit Invigor Medical
VS
Grade C · #85

Wholesome Clinic

Cost-first shoppers who want multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.

Visit Wholesome Clinic

The verdict

Winner · Invigor MedicalGrade B+ vs C

Invigor Medical takes it, leading the Cost-Efficiency Index 88 to 72. Solid mid-market cost on both molecules from an established operator — good value if you also want a broader metabolic and hormone catalog. Wholesome Clinic still earns a CCost-first shoppers who want multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Invigor Medical.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
75

Price Transparency

84
78

Nationwide Access

78
42

Formulation Options

82
90

Clinical Oversight

86
92

Contract Flexibility

87
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecInvigor MedicalWholesome Clinic
Cost-Efficiency Index88/10072/100
Semaglutide / mo$199/mo$149/mo (starting dose, compounded)
Tirzepatide / mo$339/mo$349/mo (starting dose, compounded)
Semaglutide / yr (modeled)$2,388$1,788
Tirzepatide / yr (modeled)$4,068$4,188
CoverageNot disclosed7 states
Oral / sublingualNoYes
Brand-name accessCompounded onlyYes
Rank on the board#8#85

Invigor Medical

88/100

Where the value is

  • Competitive mid-market pricing on both semaglutide and tirzepatide
  • Long-running operator with a broad catalog that can consolidate spend
  • Both molecules published up front for easy cost modeling

The tradeoffs

  • Does not publish an explicit states-served list, so access is a variable in the model
  • Compounded only
Visit Invigor Medical

Full Invigor Medical review →

Wholesome Clinic

72/100

Where the value is

  • Publishes standing per-dose self-pay prices for compounded semaglutide and tirzepatide, oral and injectable
  • Compounded semaglutide from $109/mo (oral) or $149/mo (injectable); brand Wegovy/Zepbound offered when appropriate
  • Telehealth across seven states plus an in-person option at its Frisco, TX office

The tradeoffs

  • $149 initial evaluation and $75 follow-up visits are billed separately from medication
  • Filled through your 'preferred pharmacy' — no single named compounding pharmacy partner
Visit Wholesome Clinic

Full Wholesome Clinic review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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