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Head-to-head · Cost-Efficiency Index

Invigor Medical vs Silhouette MD

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #8

Invigor Medical

Value shoppers who want competitive pricing on both molecules plus a wider wellness/hormone program on one account.

Visit Invigor Medical
VS
Grade C · #288

Silhouette MD

People who want hands-on concierge support alongside compounded GLP-1 treatment.

Visit Silhouette MD

The verdict

Winner · Invigor MedicalGrade B+ vs C

Invigor Medical takes it, leading the Cost-Efficiency Index 88 to 56. Solid mid-market cost on both molecules from an established operator — good value if you also want a broader metabolic and hormone catalog. Silhouette MD still earns a CPeople who want hands-on concierge support alongside compounded GLP-1 treatment.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Invigor Medical.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
77

Price Transparency

84
30

Nationwide Access

78
24

Formulation Options

82
77

Clinical Oversight

86
77

Contract Flexibility

87
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecInvigor MedicalSilhouette MD
Cost-Efficiency Index88/10056/100
Semaglutide / mo$199/mo$149/mo (compounded)
Tirzepatide / mo$339/mo$299/mo (compounded)
Semaglutide / yr (modeled)$2,388$1,788
Tirzepatide / yr (modeled)$4,068$3,588
CoverageNot disclosedCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyCompounded only
Rank on the board#8#288

Invigor Medical

88/100

Where the value is

  • Competitive mid-market pricing on both semaglutide and tirzepatide
  • Long-running operator with a broad catalog that can consolidate spend
  • Both molecules published up front for easy cost modeling

The tradeoffs

  • Does not publish an explicit states-served list, so access is a variable in the model
  • Compounded only
Visit Invigor Medical

Full Invigor Medical review →

Silhouette MD

56/100

Where the value is

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection

The tradeoffs

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
Visit Silhouette MD

Full Silhouette MD review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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