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Head-to-head · Cost-Efficiency Index

Invigor Medical vs CLYR Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #8

Invigor Medical

Value shoppers who want competitive pricing on both molecules plus a wider wellness/hormone program on one account.

Visit Invigor Medical
VS
Grade C · #234

CLYR Health

Cost-first shoppers who want flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up.

Visit CLYR Health

The verdict

Winner · Invigor MedicalGrade B+ vs C

Invigor Medical takes it, leading the Cost-Efficiency Index 88 to 60. Solid mid-market cost on both molecules from an established operator — good value if you also want a broader metabolic and hormone catalog. CLYR Health still earns a CCost-first shoppers who want flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Invigor Medical.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
49

Price Transparency

84
86

Nationwide Access

78
24

Formulation Options

82
90

Clinical Oversight

86
74

Contract Flexibility

87
37

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecInvigor MedicalCLYR Health
Cost-Efficiency Index88/10060/100
Semaglutide / mo$199/mo$229/mo (compounded)
Tirzepatide / mo$339/mo$249/mo (compounded)
Semaglutide / yr (modeled)$2,388$2,748
Tirzepatide / yr (modeled)$4,068$2,988
CoverageNot disclosedCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyYes
Rank on the board#8#234

Invigor Medical

88/100

Where the value is

  • Competitive mid-market pricing on both semaglutide and tirzepatide
  • Long-running operator with a broad catalog that can consolidate spend
  • Both molecules published up front for easy cost modeling

The tradeoffs

  • Does not publish an explicit states-served list, so access is a variable in the model
  • Compounded only
Visit Invigor Medical

Full Invigor Medical review →

CLYR Health

60/100

Where the value is

  • Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
  • LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
  • 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo

The tradeoffs

  • State availability gated behind intake; not published on the marketing site
  • Standing monthly rates ($229-249) run above the cheapest compounded competitors
Visit CLYR Health

Full CLYR Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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