Head-to-head · Cost-Efficiency Index
Invigor Medical vs Blue Sky MD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Invigor Medical
Value shoppers who want competitive pricing on both molecules plus a wider wellness/hormone program on one account.
Visit Invigor MedicalBlue Sky MD
Cost-first shoppers who want legitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching.
Visit Blue Sky MDThe verdict
Invigor Medical takes it, leading the Cost-Efficiency Index 88 to 64. Solid mid-market cost on both molecules from an established operator — good value if you also want a broader metabolic and hormone catalog. Blue Sky MD still earns a C — Cost-first shoppers who want legitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Invigor Medical.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Invigor Medical | Blue Sky MD |
|---|---|---|
| Cost-Efficiency Index | 88/100 | 64/100 |
| Semaglutide / mo | $199/mo | $160/mo (starting dose, compounded) |
| Tirzepatide / mo | $339/mo | $240/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $1,920 |
| Tirzepatide / yr (modeled) | $4,068 | $2,880 |
| Coverage | Not disclosed | 1 state |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #8 | #167 |
Invigor Medical
88/100Where the value is
- Competitive mid-market pricing on both semaglutide and tirzepatide
- Long-running operator with a broad catalog that can consolidate spend
- Both molecules published up front for easy cost modeling
The tradeoffs
- Does not publish an explicit states-served list, so access is a variable in the model
- Compounded only
Blue Sky MD
64/100Where the value is
- LegitScript certified and physician-led since 2008; one of the most established GLP-1 practices in the Southeast
- Compounded semaglutide from $40/week (~$160/month) and tirzepatide from $60/week (~$240/month) — well below brand-name cost
- Comprehensive program includes 1-on-1 wellness coaching, nutrition plans, hormone analysis, and a proprietary mobile app
The tradeoffs
- Geographic reach unclear — physical clinics in NC only; telehealth states beyond NC unconfirmed despite 'from virtually anywhere' claim
- Pricing quoted per-week ($40 sema / $60 tirz) rather than per-month; higher-dose pricing not disclosed
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.