Head-to-head · Cost-Efficiency Index
NewSelf vs Primary Clinic (Direct GLP)
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
NewSelf
Budget shoppers who want a verified all-50 program and one of the lowest disclosed tirzepatide prices in the value tier.
Visit NewSelfPrimary Clinic (Direct GLP)
Price-first shoppers inside its 10 served states who will do their own pharmacy diligence.
Visit Primary Clinic (Direct GLP)The verdict
NewSelf takes it, leading the Cost-Efficiency Index 87 to 77. $100 semaglutide and $144 tirzepatide, nationwide and LegitScript-verified — near-identical value to the cheapest verified names, with the tirzepatide price a hair lower than most. Primary Clinic (Direct GLP) still earns a C — Price-first shoppers inside its 10 served states who will do their own pharmacy diligence.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs NewSelf.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | NewSelf | Primary Clinic (Direct GLP) |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 77/100 |
| Semaglutide / mo | $100/mo | $65/mo |
| Tirzepatide / mo | $144/mo | $110/mo |
| Semaglutide / yr (modeled) | $1,200 | $780 |
| Tirzepatide / yr (modeled) | $1,728 | $1,320 |
| Coverage | All 50 states | WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #6 | #25 |
NewSelf
87/100Where the value is
- $100 semaglutide / $144 tirzepatide — one of the cheapest verified combined prices on the board
- Nationwide all-50 coverage with both molecules published up front
- LegitScript-certified pharmacy behind the low price
The tradeoffs
- Compounded only — no brand-name or oral option
- Newer consumer brand with a thin public track record
Primary Clinic (Direct GLP)
77/100Where the value is
- The lowest disclosed sticker prices anywhere on the board — $65 semaglutide / $110 tirzepatide
- Both molecules published for clear cost modeling
- Exceptional raw cost-per-month if you live in a served state
The tradeoffs
- Only 10 states served — a coverage gamble that guts its nationwide-access score
- Not LegitScript-certified
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.