Head-to-head · Cost-Efficiency Index
Breeze Meds vs Semaglutide Online
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Breeze Meds
People who want to independently verify the clinicians and pharmacy behind their GLP-1 — and who'll pay a mid-market price for that paper trail plus FSA/HSA eligibility.
Visit Breeze MedsSemaglutide Online
Cost-first shoppers who want legitScript GLP-1 nationwide ex. AL; compounded sema $199 or tirz $299/mo all-in; financing from $79/mo.
Visit Semaglutide OnlineThe verdict
Breeze Meds takes it, leading the Cost-Efficiency Index 86 to 82. The most transparent operator in our partner tier — all-50 compounded GLP-1 with NPI-verifiable named physicians, named pharmacies and LegitScript backing, so you can actually audit who's behind the script. Semaglutide Online still earns a B− — Cost-first shoppers who want legitScript GLP-1 nationwide ex. AL; compounded sema $199 or tirz $299/mo all-in; financing from $79/mo.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Breeze Meds.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Breeze Meds | Semaglutide Online |
|---|---|---|
| Cost-Efficiency Index | 86/100 | 82/100 |
| Semaglutide / mo | $199/mo | $199/mo (all doses, compounded) |
| Tirzepatide / mo | $399/mo | $299/mo (all doses, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,388 |
| Tirzepatide / yr (modeled) | $4,788 | $3,588 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Yes |
| Rank on the board | #5 | #32 |
Breeze Meds
86/100Where the value is
- Best transparency of this partner batch — NPI-verifiable named physicians (Lion MD group), named dispensing pharmacies, and LegitScript certification
- All 50 states, with injectable semaglutide from $199/mo plus oral semaglutide (~$299) and oral tirzepatide (~$399) for the needle-averse
- FSA/HSA eligible, which trims the effective monthly cost
The tradeoffs
- Mid-to-higher per-month pricing — tirzepatide and the oral routes carry a premium over the cheapest all-50 rivals
- Compounded only — not FDA-approved brand-name medication
Semaglutide Online
82/100Where the value is
- LegitScript certified — passes accreditation standards recognized by Google and Visa for online telehealth
- Compounded all-in pricing: semaglutide $199/mo and tirzepatide $299/mo includes medication, provider care, and shipping
- Brand-name options (Wegovy pill, injectable sema, Zepbound) available for eligible patients, potentially $0-$25/mo with insurance
The tradeoffs
- No labs or clinical monitoring disclosed — blood work requirements not mentioned anywhere on site
- Leadership team and medical director not identified on site — no named prescribers or company founders published
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.