Head-to-head · Cost-Efficiency Index
Vitara RX vs Piper
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Vitara RX
Value-first shoppers who want the cheapest all-50 price on both molecules and refuse to trade away pharmacy verification to get it.
Visit Vitara RXPiper
Nationwide shoppers who want both molecules disclosed at fair prices and will do their own diligence on the pharmacy.
Visit PiperThe verdict
Vitara RX takes it, leading the Cost-Efficiency Index 87 to 82. $99 semaglutide and $149 tirzepatide, all-50 and LegitScript-verified — the rare budget roster spot that undercuts the field without dropping a molecule or its pharmacy credentials. Piper still earns a B− — Nationwide shoppers who want both molecules disclosed at fair prices and will do their own diligence on the pharmacy.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Vitara RX.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Vitara RX | Piper |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 82/100 |
| Semaglutide / mo | $99/mo | $135/mo |
| Tirzepatide / mo | $149/mo | $199/mo |
| Semaglutide / yr (modeled) | $1,188 | $1,620 |
| Tirzepatide / yr (modeled) | $1,788 | $2,388 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #5 | #22 |
Vitara RX
87/100Where the value is
- $99 semaglutide and $149 tirzepatide — among the lowest combined prices on the board, and cheaper on tirzepatide than most sub-$100-sema rivals
- Nationwide all-50 access with both molecules disclosed for clean year-one cost modeling
- LegitScript-certified — budget pricing without the unverified-pharmacy asterisk that dogs the cheapest tier
The tradeoffs
- Compounded only — no FDA-approved brand-name or oral/sublingual route
- Lower-profile newcomer without a long public track record
Piper
82/100Where the value is
- Both molecules disclosed — $135 semaglutide / $199 tirzepatide — for clean cost modeling
- Nationwide all-50 access with predictable flat pricing
- Straightforward to model for a full year
The tradeoffs
- Not LegitScript-certified, so pharmacy oversight is harder to verify
- Compounded only — no brand-name or oral route
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.