Head-to-head · Cost-Efficiency Index
ShedRx vs Shed (tryshed.com)
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ShedRx
People who want the cheapest disclosed tirzepatide or an oral option without giving up a modelable flat price.
Visit ShedRxShed (tryshed.com)
People who want to try alternative formats (drops, lozenges, microdose) or a brand pill under one named care team, with a money-back window to de-risk the commitment.
Visit Shed (tryshed.com)The verdict
ShedRx takes it, leading the Cost-Efficiency Index 87 to 85. The lowest published tirzepatide cost among our partners, plus an oral/sublingual route — strong cost-per-month for the needle-averse. Shed (tryshed.com) still earns a B — People who want to try alternative formats (drops, lozenges, microdose) or a brand pill under one named care team, with a money-back window to de-risk the commitment.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ShedRx | Shed (tryshed.com) |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 85/100 |
| Semaglutide / mo | $199/mo | $159/mo |
| Tirzepatide / mo | $299/mo | $239/mo |
| Semaglutide / yr (modeled) | $2,388 | $1,908 |
| Tirzepatide / yr (modeled) | $3,588 | $2,868 |
| Coverage | Not disclosed | Not disclosed |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Yes |
| Rank on the board | #4 | #10 |
ShedRx
87/100Where the value is
- Lowest published tirzepatide price of our partner tier at $299/mo
- Offers oral/sublingual forms — more formulation options per dollar
- Both molecules disclosed for straightforward cost comparison
The tradeoffs
- States-served not disclosed
- Compounded only
Shed (tryshed.com)
85/100Where the value is
- Unusually wide formats — compounded injections plus drops, lozenges and microdosing, and a brand Wegovy pill (~$149) for the needle-averse
- Named care team (Dr. Asad Niazi plus a nurse, dietitian and coach) rather than an anonymous clinician pool
- 120-day money-back guarantee lowers the risk of committing
The tradeoffs
- The novel formats (drops, lozenges, microdose) haven't been evaluated by the FDA for this use
- No LegitScript certification, founding year or parent company published, so verification is thinner
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.