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Head-to-head · Cost-Efficiency Index

NewSelf vs Ro

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #6

NewSelf

Budget shoppers who want a verified all-50 program and one of the lowest disclosed tirzepatide prices in the value tier.

Visit NewSelf
VS
Grade B · #19

Ro

People who need brand-name (Wegovy/Zepbound) access or insurance navigation and will accept price opacity for it.

Visit Ro

The verdict

Winner · NewSelfGrade B+ vs B

NewSelf takes it, leading the Cost-Efficiency Index 87 to 84. $100 semaglutide and $144 tirzepatide, nationwide and LegitScript-verified — near-identical value to the cheapest verified names, with the tirzepatide price a hair lower than most. Ro still earns a BPeople who need brand-name (Wegovy/Zepbound) access or insurance navigation and will accept price opacity for it.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs NewSelf.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

94
74

Price Transparency

87
72

Nationwide Access

96
85

Formulation Options

78
93

Clinical Oversight

86
90

Contract Flexibility

82
84

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNewSelfRo
Cost-Efficiency Index87/10084/100
Semaglutide / mo$100/moNot disclosed
Tirzepatide / mo$144/moNot disclosed
Semaglutide / yr (modeled)$1,200
Tirzepatide / yr (modeled)$1,728
CoverageAll 50 statesMulti-state
Oral / sublingualNoYes
Brand-name accessCompounded onlyYes
Rank on the board#6#19

NewSelf

87/100

Where the value is

  • $100 semaglutide / $144 tirzepatide — one of the cheapest verified combined prices on the board
  • Nationwide all-50 coverage with both molecules published up front
  • LegitScript-certified pharmacy behind the low price

The tradeoffs

  • Compounded only — no brand-name or oral option
  • Newer consumer brand with a thin public track record
Visit NewSelf

Full NewSelf review →

Ro

84/100

Where the value is

  • Brand-name access and insurance support
  • Oral options widen the formulary
  • Polished, well-funded platform

The tradeoffs

  • Does not publish compounded pricing up front — a blind spot in any cost model
  • Premium positioning
Visit Ro

Full Ro review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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