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Head-to-head · Cost-Efficiency Index

NewSelf vs NP2GO

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #6

NewSelf

Budget shoppers who want a verified all-50 program and one of the lowest disclosed tirzepatide prices in the value tier.

Visit NewSelf
VS
Grade C · #24

NP2GO

Shoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves.

Visit NP2GO

The verdict

Winner · NewSelfGrade B+ vs C

NewSelf takes it, leading the Cost-Efficiency Index 87 to 79. $100 semaglutide and $144 tirzepatide, nationwide and LegitScript-verified — near-identical value to the cheapest verified names, with the tirzepatide price a hair lower than most. NP2GO still earns a CShoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs NewSelf.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

94
79

Price Transparency

87
79

Nationwide Access

96
84

Formulation Options

78
77

Clinical Oversight

86
76

Contract Flexibility

82
80

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNewSelfNP2GO
Cost-Efficiency Index87/10079/100
Semaglutide / mo$100/mo$150/mo
Tirzepatide / mo$144/mo$250/mo
Semaglutide / yr (modeled)$1,200$1,800
Tirzepatide / yr (modeled)$1,728$3,000
CoverageAll 50 statesAK, AZ, AR, CA, CO, CT, DE, DC, FL, HI, ID, IL, IA, KS, KY, ME, MD, MA, MI, MN, MT, NE, NV, NH, NJ, NM, NY, ND, OK, OR, PA, RI, SD, TX, UT, VT, VA, WA, WV, WY
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank on the board#6#24

NewSelf

87/100

Where the value is

  • $100 semaglutide / $144 tirzepatide — one of the cheapest verified combined prices on the board
  • Nationwide all-50 coverage with both molecules published up front
  • LegitScript-certified pharmacy behind the low price

The tradeoffs

  • Compounded only — no brand-name or oral option
  • Newer consumer brand with a thin public track record
Visit NewSelf

Full NewSelf review →

NP2GO

79/100

Where the value is

  • Both molecules disclosed — $150 semaglutide / $250 tirzepatide — for straightforward cost modeling
  • Broad 40-state footprint — wider than most non-nationwide operators
  • Flat, predictable pricing

The tradeoffs

  • 40 states, not all 50 — a coverage gamble that dents its access score
  • Not LegitScript-certified — oversight harder to verify
Visit NP2GO

Full NP2GO review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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