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Head-to-head · Cost-Efficiency Index

Ondra Health vs Shed (tryshed.com)

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A− · #3

Ondra Health

Value shoppers who want one of the lowest disclosed prices on both molecules without giving up nationwide access or pharmacy verification.

Visit Ondra Health
VS
Grade B · #10

Shed (tryshed.com)

People who want to try alternative formats (drops, lozenges, microdose) or a brand pill under one named care team, with a money-back window to de-risk the commitment.

Visit Shed (tryshed.com)

The verdict

Winner · Ondra HealthGrade A− vs B

Ondra Health takes it, leading the Cost-Efficiency Index 90 to 85. A rare combination — near-rock-bottom pricing on both molecules, all-50 access, brand-name availability, and a LegitScript-verified pharmacy behind it. Shed (tryshed.com) still earns a BPeople who want to try alternative formats (drops, lozenges, microdose) or a brand pill under one named care team, with a money-back window to de-risk the commitment.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Ondra Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

94
85

Price Transparency

88
83

Nationwide Access

96
82

Formulation Options

86
90

Clinical Oversight

88
82

Contract Flexibility

88
88

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecOndra HealthShed (tryshed.com)
Cost-Efficiency Index90/10085/100
Semaglutide / mo$93/mo$159/mo
Tirzepatide / mo$166/mo$239/mo
Semaglutide / yr (modeled)$1,116$1,908
Tirzepatide / yr (modeled)$1,992$2,868
CoverageAll 50 statesNot disclosed
Oral / sublingualNoYes
Brand-name accessYesYes
Rank on the board#3#10

Ondra Health

90/100

Where the value is

  • Among the lowest disclosed prices on the board — $93 semaglutide and $166 tirzepatide
  • Available in all 50 states with both molecules published for clean cost modeling
  • LegitScript-certified, and offers FDA-approved brand-name access alongside compounded

The tradeoffs

  • A newer, lower-profile operator without CoreAge's long flat-price track record
  • No oral/sublingual route
Visit Ondra Health

Full Ondra Health review →

Shed (tryshed.com)

85/100

Where the value is

  • Unusually wide formats — compounded injections plus drops, lozenges and microdosing, and a brand Wegovy pill (~$149) for the needle-averse
  • Named care team (Dr. Asad Niazi plus a nurse, dietitian and coach) rather than an anonymous clinician pool
  • 120-day money-back guarantee lowers the risk of committing

The tradeoffs

  • The novel formats (drops, lozenges, microdose) haven't been evaluated by the FDA for this use
  • No LegitScript certification, founding year or parent company published, so verification is thinner
Visit Shed (tryshed.com)

Full Shed (tryshed.com) review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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